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Combinatorial procedures have become established in recent years as alternatives to rational design in drug research, particularly when no structural information is available. This article presents the principle that was… Click to show full abstract
Combinatorial procedures have become established in recent years as alternatives to rational design in drug research, particularly when no structural information is available. This article presents the principle that was originally developed by three scientists and was honored with the Nobel Prize for Chemistry in 2018. Furthermore, the application in the field of monclonal antibodies is discussed.
Keywords:
drug;
application;
directed evolution;
evolution drug;
nobel prize
Journal Title: Der Internist
Year Published: 2019
Link to full text (if available)
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Journal Title: Der Internist
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!