LAUSR

During the treatment of an acute lymphoblastic leukemia, a 40-year-old man developed a fever and was admitted to the intensive care unit because of septic shock and respiratory failure. He presented with metastatic skin lesions (Fig. 1a), and a computed tomography found diffuse pulmonary micronodules (Fig. 1b). Two blood cultures grew on the fourth day and direct microscopic examination showed fungal hyphae (Fig. 2a). The culture of the skin punch identified arthroconidia and blastoconidia (Fig. 2b) suggesting Trichosporon species. Trichosporon inkin was identified by MALDI-TOF mass spectrometry in both samples and in pleural fluid. Fundoscopy revealed bilateral chorioretinitis, but transesophageal echocardiography did not find endocarditis. The patient received prolonged intravenous voriconazole, and his condition slowly improved. In recent years, Trichosporon has emerged as an important opportunistic pathogen in immunocompromised individuals. As this yeast is resistant to echinocandins and flucytosine, and considering that poor