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Multiple vertebral fractures as the first manifestation of systemic mastocytosis

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Systemic mastocytosis is a clonal disease of the mast cell progenitors of the bone marrow. The clinical picture varies from asymptomatic (indolent) to highly aggressive (mast cell leukemia). Up to… Click to show full abstract

Systemic mastocytosis is a clonal disease of the mast cell progenitors of the bone marrow. The clinical picture varies from asymptomatic (indolent) to highly aggressive (mast cell leukemia). Up to one-third of patients with SM have osteoporosis and fractures. The following is an analysis of the case of a young patient with multiple fractures as the first manifestation of SM.

Keywords: multiple vertebral; fractures first; systemic mastocytosis; first manifestation

Journal Title: Osteoporosis International
Year Published: 2019

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