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World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2019): ESCEO Symposia Abstracts # International Osteoporosis Foundation and National Osteoporosis Foundation 2019 ESCEO1 IDENTIF ICAT ION PRIORIT IZAT ION OF IMPORTANTATTRIBUTES OF OATREATMENT E. M. Dennison, on behalf of the ESCEOWorking Group on patients’ preferences for anti-osteoarthritis treatment: a crossEuropean Discrete Choice Experiment MRC Lifecourse Epidemiology Unit, Southampton, United Kingdom In recent years, there has been a growing interest in obtaining patients’ preferences for healthcare treatments that are deemed ‘preference sensitive’. In particular, the use of statedpreference studies, including discrete-choice experiments (DCE), has markedly increased. Preference sensitive treatments are those in which there are trade-offs between health benefits and risks. Previous studies of this kind that have focused on osteoarthritis (OA) treatment have suggested that OA patients are most concerned about efficacy and risks of therapy. Further insights into the preferences of patients will be useful to optimize policy and clinical decision making through healthcare decision making that better reflects patients’ preferences. An important step in the conduct of a DCE is the identification and selection of attributes. We therefore followed a four-step process. First a literature review was undertaken by 2 researchers to identify potential outcomes that might be important to OA patients. Second, individual interviews with OA patients and experts were made to identify further outcomes. Third, based on the list of 26 identified outcomes, a survey was conducted with 56 OA patients from seven European countries to ask them to identify and prioritize the most important characteristics regarding OA treatment. Finally, the final list of outcomes was agreed at an expert meeting (n = 11), held in March 2018. The expert group agreed on seven attributes to be included in the DCE: improvement in pain, improvement in walking, ability to manage domestic activities (such as cooking, cleaning, gardening), ability to manage social activities (such as playing games, belonging to social groups, or traveling), improvement in overall energy and wellbeing, risk of moderate/severe side effects and impact on disease progression. ESCEO2 A CROSS-EUROPEAN DISCRETE CHOICE EXPERIMENT TO ELICIT PATIENTS’ PREFERENCES FOR OSTEOARTHRITIS TREATMENT M. Hiligsmann, on behalf of the ESCEO Working Group on patients’ preferences for anti-osteoarthritis treatment: a crossEuropean Discrete Choice Experiment Department of Health Services Research, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands This study aims to evaluate the preferences of patients for antiosteoarthritis treatment by establishing how they trade between the seven previously identified outcomes using a discretechoice experiment (DCE). In the DCE survey, patients were repetitively asked to choose which one of two treatment options (Treatment A and Treatment B) they would prefer. The two treatment differs in seven attributes, i.e. improvement in pain, improvement in walking, ability to manage domestic activities (such as cooking, cleaning, gardening), ability to manage social activities (such as playing games, belonging to social groups, or traveling), improvement in overall energy and well-being, risk of moderate/severe side effects and impact on disease progression. An efficient experimental design was used to construct the 12 choice sets and the self-completed paper questionnaire was pilot tested with about 20 osteoarthritis patients to check interpretation problems and face validity. The DCE is thereafter conducted in about 250 patients with knee and/or hip osteoarthritis recruited in UK, France, Belgium, Italy, Netherlands, Portugal and Spain. Osteoporosis International (2019) 30 (Suppl 2):S185–S190 https://doi.org/10.1007/s00198-019-04982-z