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World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2019): Posters Abstracts # International Osteoporosis Foundation and National Osteoporosis Foundation 2019 P101 EFFECT OF ERAS ASSISTED MIPPO IN THE TREATMENTOF PROXIMALHUMERALFRACTURE W. Ji, B. Weiguo Department of Orthopaedics, The First Affiliated Hospital of Xi’an Jiaotong University, Xian, China Objective: To investigate the effect of ERAS combined with MIPPO in the treatment of proximal humerus fracture. Method: 32 patients with proximal humerus fractures were randomly divided into ERAS combined with MIPPO group and simple MIPPO group that have 16 cases each. These two kinds of groups have same operation, while the treatment before and after operation were very different. The VAS score, the incidence of complications, the average hospitalization days and cost, the time of beginning to walk postoperatively and functional exercise were compared between these two groups. Results:ComparedwithMIPPO group, the VAS score of ERAS combined with MIPPO group was lower than that of MIPPO group. The incidence of nausea and vomiting was 12.5% vs. 43.75%. The average hospitalization day was 5.7±1.3 d vs. 8.2 ±1.4 d, the average hospitalization cost was 3.1±0.8 w vs. 3.9±0.6 w. The time of beginning to walk postoperatively was 6.2±0.8 h vs. 24.2±2.7 h while the time of beginning functional exercise after operation was 2.1±0.4 d vs. 7.2±1.2 d (P<0.05). Conclusion: ERAS combined with MIPPO can alleviate postoperative pain, reduce postoperative complications, shorten average hospitalization days and cost, bring forward days of walking and functional exercise, which is better for patients’ recovery and is worthy for clinical application. P102 CLASSIFICATIONALGORITHMS FOR PREDICTING THE RISK OF OSTEOPOROTIC FRACTURE H. Kim Gachon University, Seoul, South Korea Information technology may provide alternative approaches to osteoporosis disease diagnosis. This systematic reviewwas performed to compare the diagnostic accuracy of vertebral fracture assessment. In this study, we examined the potential use of classification techniques on a massive volume of healthcare data, particularly in prediction of patients that may have osteoporosis through its risk factors. For this purpose, we proposed to develop a new solution approach based on random forest decision tree to identify the osteoporosis cases. There has been no research in using the aforementioned algorithm for osteoporosis patient prediction. The reduction of the attributes consisted to enumerate dynamically the optimal subsets of the reduced attributes of high interest by reducing the degree of complexity. A computer-aided system was developed for this purpose. The performance of the proposed model in this study was analyzed and evaluated based on set of benchmark techniques applied in this classification problem. P103 L3 VERTEBRAL BODY COMPRESSION FRACTURE IN A PATIENT WITH TYPE 2 DIABETES MELLITUS AND VITAMIN B12 DEFICIENCY – RISK FACTORS ASSESSMENTAND THE ROLE OF DENOSUMAB IN ITS CONTROL: CLINICAL CASE PRESENTATION A. Holub, J. Marante Fuertes Hospital of Jerez de la Frontera, La Granja First Care Center, Orthopeadic and Traumatology Department, Hospital of Jerez de la Frontera, Cadiz, Spain Objectives: Vertebral compression fractures are very common especially in older adults and are usually caused by osteoporosis where mineral bone density became low. This kind of fractures is a growing public health problem with important socioeconomic effects in the western countries. Osteoporotic fractures are those occurring from a fall from a standing height or less, without major trauma. They often occur at the midthoracic (T7-T8) spine and the thoracolumbar junction (T12-L1). Fractures may result in significant back pain, leading to inability to perform activities of daily living. and can lead to loss of independence, depression, and chronic pain. Osteoporotic fracture is an important risk factor for subsequent fracture. While the diagnosis can be suspected from history and physical examination, plain radiography, as well as occasional CTor MRI, https://doi.org/10.1007/s00198-019-04993-w Osteoporosis International (2019) 30 (Suppl 2):S –S 253 773