LAUSR

Book’s topic The combination of separation sciences with mass spectrometry (MS), using soft ionization, has established itself as a key analytical technique in many disciplines including: pharmaceuticals, medicine, biology, environmental and food sciences. Soft ionization such as electrospray or atmospheric pressure chemical ionization generate mainly protonated or deprotonated molecules and adducts ions. Fragmentation of the even electron ions can be obtained by collision induced dissociation with a neutral gas. Tremendous development in mass spectrometry hardware combining different type of mass analysers have made tandem mass spectrometry a routine technique. Contrary, to peptides, product ion spectra of low molecular weight compounds cannot be easily predicted by bioinformatics making structural elucidation by mass spectrometry challenging. While for electron impact the fragmentation rules of odd electron ions have been extensively investigated and rules established, very little is known about the fragmentation of even electron ions. The book Interpretation of MS-MS mass spectra of drugs and pesticides by Wilfried M. A. Niessen and Ricardo A. Correra C. is a welcome reference which provides comprehensive and advanced insights in the use of tandem mass spectrometry. A special attempt has been made to the understanding of the fragmentation of a large variety of drugs and pesticides based on chemical structure similarities by renowned experts on the subject with extensive references of current literature.