LAUSR

Scientific Abstracts 8th Phoenix Fetal Cardiology Symposium October 27–31, 2017 Sponsored by Phoenix Children’s Hospital, Phoenix, AZ Springer Science+Business Media, LLC, part of Springer Nature 2017 Normal Reference Ranges for Cardiac Valve CrossSectional Areas in Preterm Infants Abushaban, Lulu, Thinakar, Mariappa, Rathinasamy Jebaraj, Sharma, Prem Chest Diseases Hospital, Kuwait University; Chest Diseases Hospital, Ministry of Health Objective: To establish normal reference ranges for cardiac valve cross-sectional areas in preterm infants and their correlation with gestational age, body weight, and chronological age. Subjects and Methods: In a prospective study, 268 preterm babies, who fulfilled the criteria for inclusion, were examined. Echocardiograms were performed to measure aortic, pulmonary, mitral, and tricuspid valve cross-sectional areas over 0–6 day(s) of life and at weekly intervals until they reached 36 weeks. The gestational age was grouped into three: (24–27), (28–31), and (32–35) weeks, and body weight into five: B, 999, 1000–1499, 1500–1999, 2000–2499, and C 2500 g. The overall group differences were compared for each period of life: (0–6) days, 1–2, 3–4, and C 5 weeks. Results: The mean gestational age was 29.8 (± 2.38 SD) weeks, ranging between 24 and 35, and the mean body weight 1479 (± 413 SD) grams, ranging between 588 and 3380. All the cardiac valve cross-sectional areas correlated well with body weight. A significant gradual increase was noticed in all valve cross-sectional areas with body weight during each period of life. Overall, a progressive and significant increase for all valve cross-sectional areas was observed during the first nine weeks of life. Conclusion: The cardiac valve cross-sectional areas were found to have significant correlation with body weight. The study also provides reference data, which can be used as normal reference tool for valve cross-sectional areas for preterm infants against the gestational age, body weight, and chronological age. Umbilical Cord Blood Gas Analyses in Newborns Prenatally Diagnosed with Congenital Heart Disease Aggarwal, Nimisha MD, Adams, April MD, MS, Tague, Lauren MD, Iqbal, Sara N MD, FACOG, Skurow-Todd, Kami MSN, McCarter, Robert ScD, Donofrio, Mary T MD Division of Cardiology, Children’s National Health System, Washington, DC; Division of Maternal Fetal Medicine, MedStar Washington Hospital Center; Division of Biostatistics and Study Methodology, Children’s National Health System, Washington, DC Background: Umbilical cord blood gas analysis is recommended for high-risk deliveries to provide vital information regarding the fetal circulation, clinical status at delivery, and predicted postnatal outcome. Limited data are available in newborns with congenital heart disease (CHD). Our purpose was to compare cord blood gas data in newborns prenatally diagnosed with CHD to healthy newborns and determine if specific CHD subtype was associated with fetal acidosis. Methods: Retrospective review was undertaken of fetal echocardiograms and delivery room records of patients prenatally diagnosed with CHD. CHD patients compared to a control group which included singleton deliveries without CHD chosen by a random number generator to match the year of birth to the CHD population. Data recorded included CHD diagnosis, mode of delivery, and umbilical cord arterial gas results. Results: 176 CHD newborns, 146 controls. Mean pH in CHD fetuses was 7.22 (CI 7.2–7.4) and in controls was 7.22 (CI 7.21–7.24) (p = 0.91). There was no difference in mean pH between those with single ventricle CHD 7.23 (CI 7.2–7.26) and those with two ventricle CHD (7.22–7.24) (p = 0.77). There was also no difference in those with CHD with aortic obstruction 7.23 (7.21–7.26) and those without aortic obstruction 7.22 (CI 7.2–7.24) (p = 0.29). Mean arterial pH in the induced vaginal delivery group was lower than that in the 123 Pediatr Cardiol (2018) 39:198–201 https://doi.org/10.1007/s00246-017-1774-7