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What radiologists should know about microRNA (miRNA) serum biomarkers for germ cell tumors

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MicroRNAs expressed by germ cell tumors represent a novel approach to detection of metastatic disease during staging, surveillance, and recurrence post-therapy. It has particular promise in settings of equivocal imaging,… Click to show full abstract

MicroRNAs expressed by germ cell tumors represent a novel approach to detection of metastatic disease during staging, surveillance, and recurrence post-therapy. It has particular promise in settings of equivocal imaging, such as clinical stage I GCT, tumor marker negative stage IIA, or after chemotherapy. These miRNAs have the potential to change typical serum marker evaluation and imaging surveillance schedules.

Keywords: radiologists know; serum; germ cell; cell tumors; know microrna

Journal Title: Abdominal Radiology
Year Published: 2020

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