LAUSR

Abbreviations ALK Anaplastic lymphoma kinase ATF Activating transcription factor BCSC Breast cancer stem cells CHOP CCAAT-enhancer-binding protein homologous protein CPI Checkpoint inhibitor EMA European medicines agency EML4 Microtubule-associated protein-like 4 EV Extracellular vesicles FLIP FLICE-inhibitory protein GO Gemtuzumab ozogamicin GPCRs Protein-coupled receptors HNSCC Head and neck squamous cell carcinoma ICIs Immune checkpoint inhibitors ICIR Immune checkpoint inhibitory receptor irAEs Immune-related adverse events iTreg Induced regulatory T cell miTRAP miRNA trapping by RNA in vitro affinity purification MM Multiple myeloma NSCLC Non-small cell lung cancer NTRK Neurotrophic tropomyosin receptor kinase PARP Poly (ADP-ribose) pTreg Peripheral Treg TEX Tumor-derived exosomes TIGIT T-cell immunoglobulin and ITIM domain TIM-3 T-cell immunoglobulin, mucin domain-3 TLS Tertiary lympoid structure TME Tumor microenvironment TP53 Tumor protein 53 Treg T regulatory cells UPR Unfolded protein response VLP Virus-like particles