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Introduction Percutaneous hepatic perfusion (PHP) with melphalan is an effective treatment for patients with hepatic metastases, but associated with high rates of bone marrow depression. To reduce systemic toxicity, improvements… Click to show full abstract
Introduction Percutaneous hepatic perfusion (PHP) with melphalan is an effective treatment for patients with hepatic metastases, but associated with high rates of bone marrow depression. To reduce systemic toxicity, improvements have been made to the filtration system. In pre-clinical studies, the Delcath System’s GEN2 filter was superior to the first-generation filters. In this clinical study, we analysed the pharmacokinetics and toxicity of PHP using the new GEN2 filter.
Keywords:
system;
hepatic perfusion;
delcath system;
melphalan;
percutaneous hepatic
Journal Title: Cardiovascular and Interventional Radiology
Year Published: 2017
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Journal Title: Cardiovascular and Interventional Radiology
Year Published: 2017
Link to full text (if available)
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recommendations!