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Successful treatment of prokinetic-resistant intestinal pseudo-obstruction and pneumatosis cystoides intestinalis in systemic sclerosis with metronidazole

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conventional prokinetics, but also octreotide. In prokinetic drug-resistant cases, antibiotics are administrated to inhibit bacterial overgrowth. However, the optimal choice and dosage of antibiotics and duration of treatment remains unclear… Click to show full abstract

conventional prokinetics, but also octreotide. In prokinetic drug-resistant cases, antibiotics are administrated to inhibit bacterial overgrowth. However, the optimal choice and dosage of antibiotics and duration of treatment remains unclear [1, 4]. We describe herein a case of SSc in which prokinetic-resistant intestinal pseudo-obstruction and PCI developed, and prompt response was obtained using metronidazole. The presented case could provide a new insight to treatment approaches for prokinetic-resistant pseudoobstruction and PCI in SSc.

Keywords: pseudo obstruction; treatment; prokinetic resistant; resistant intestinal; intestinal pseudo

Journal Title: Rheumatology International
Year Published: 2017

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