LAUSR

To evaluate the application effect of remote interventions based on digital health technology in kidney transplant patients through a systematic review. Systematic review. The databases of PubMed, Embase, Cochrane Library, CINAHL, and Web of Science were systematically searched for randomized controlled trials and quasi - experimental studies on remote interventions based on digital health technology in kidney transplant recipients. The search time limit ranged from the establishment of the databases to September 2024. A total of 10 articles were included, involving 535 patients. A total of 21 clinical outcomes were identified in this study and they were classified into three categories, namely: ① Health-related conditions: Number of steps (n = 1), heart rate (n = 1), self-burden score (n = 1), self-management ability (n = 1), quality of life score (n = 2), Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) (n = 1), psychological distress (n = 1). ② Medication adherence and average tacrolimus concentration: Medication adherence (n = 5), number of missed doses (n = 1), medication errors (n = 1), rejection reactions (n = 1), average creatinine level (n = 1), tacrolimus blood concentration level (n = 2), within-patient variability of tacrolimus (n = 1), coefficient of variation (CV) of tacrolimus (n = 1). ③ Medical economic status: Nursing satisfaction (n = 1), incidence of adverse events (n = 1), rate of unplanned hospitalization (n = 3), duration of unplanned hospitalization (n = 1), one-year medical cost (n = 2), nursing cost (n = 1). Remote interventions based on digital health technology can improve the health - related conditions, medication adherence and medical economic status of kidney transplant recipients. However, its impact on tacrolimus concentration remains unclear. Clinical medical staff should fully recognize its positive effects. 1. With growing transplant demand and limited health care resources, effective digital health interventions can facilitate self-management and monitoring of kidney transplant recipients. 2. However, the impact of remote interventions based on digital health technologies on patient health improvement is still controversial and requires comprehensive and specific analysis. 1. This study identified that remote intervention based on digital health technology can improve health-related status, medication compliance, and medical economic status of kidney transplant recipients. 2. At present, the impact of remote intervention based on digital health technology on the blood concentration of tacrolimus is not clear, and relevant research can be carried out in the future. 1. Clinical healthcare professionals should be fully aware of the beneficial effects of remote interventions based on digital health technologies on patients. 2. Active clinical development in order to improve patients’ self-care ability, reduce economic and medical burden, improve quality of life.