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A human milk-mimicking fluid for PIV experiments

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It is essential to formulate a refractive index (RI)-matched fluid to use in silicone phantom models for particle image velocimetry (PIV) experiments. In this work, an extensive effort to develop… Click to show full abstract

It is essential to formulate a refractive index (RI)-matched fluid to use in silicone phantom models for particle image velocimetry (PIV) experiments. In this work, an extensive effort to develop a non-Newtonian human milk-mimicking fluid (HMMF) with different concentrations of sodium iodide (NaI), glycerol (Gly), xanthan gum (XG), and distilled water (DW) is conducted. Measurements of RI and density are fitted onto a linear empirical expression relating to the NaI and Gly concentration. The Cross model was utilized to find the nonlinear viscosity model of raw human milk. HMMF solution is generated from a multi-constrained optimization. The matched HMMF, suitable for use in the lactating human breast phantom with bifurcated ductal structures, is achieved with composition of 15.69% NaI, 30.27% Gly, 54.02% water and 0.02% XG by weight percentage resulting in a non-Newtonian viscosity matched with that of human milk.

Keywords: milk; mimicking fluid; milk mimicking; piv experiments; human milk

Journal Title: Experiments in Fluids
Year Published: 2020

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