LAUSR

Cyclopia, derived from the term cyclops, is a rare and serious fetal anomaly in which the eyes are fused together, as a result of failure of splitting of the eye field and overgrowth of the first visceral arch (Fig. 1 and Cover) [1, 2]. Embryologically, the two orbits are fused into a single cavity containing a single or two eyeball(s) and there is a small anterior fossa of the skull cavity associated with a single optic nerve and cerebral mass [1 ] . Cyc lop i a a s soc i a t ed wi th hyd rocepha ly, holoprosencephaly, or anencephaly is a severe malformation of the brain incompatible with survival [1, 2]. This anomaly is a rich source of mythology because of its dramatic impact on societies for centuries, as revealed in the following legends [2]. Cyclopic mythic giants: Homeric Polyphemus, Turkish Tepegöz, and Anglo-Saxon Grendel