LAUSR

Nano-hydroxyapatite (HA) was successfully treated by three different surface modification methods of oleic acid (OA), silane coupling agent γ-aminopropyl triethoxysilane (KH550), and ethenyltrimethoxysilane (YDH171), respectively. Then, the treated HA and unmodified HA with 8 wt% were introduced into PLGA/PTMC blends, respectively. And the fracture morphology, thermal property, crystallization behavior, mechanical properties, surface wettability, and in vitro bioactivity of PLGA/PTMC/HA ternary composites were investigated. The results showed that the PLGA/PTMC/HA composite with the HA surface modified by OA had the highest mechanical properties, while the PLGA/PTMC/HA composite with the HA treated by silane coupling agent YDH171 had the excellent toughness, compared to the other samples. Moreover, the cells’ proliferation results confirmed that the ternary composites exhibited better biocompatibility. All the results suggested that the surface modification of HA was an ideal method in this study, and they would be potential to be used in the field of bone repair in the future.