This study aimed to evaluate the safety and efficacy of mechanical thrombectomy (MT) in patients with acute basilar artery occlusion (BAO) based on the baseline Basilar Artery on Computed Tomography… Click to show full abstract
This study aimed to evaluate the safety and efficacy of mechanical thrombectomy (MT) in patients with acute basilar artery occlusion (BAO) based on the baseline Basilar Artery on Computed Tomography Angiography (BATMAN) score. We selected patients from the BASILAR study and analyzed the effects and safety of standard medical therapy (SMT) and MT for patients with documented BATMAN scores. The patients were subgrouped according to their BATMAN score (0–3, 4–6, and 7–10). The primary outcome was a favorable functional outcome (modified Rankin Scale [mRS] ≤ 3) and mortality after 90 days. This study included 828 patients: 337 with poor BATMAN scores (0–3), 386 with moderate BATMAN scores (4–6), and 105 with good BATMAN scores (7–10). MT was associated with favorable functional outcomes in the poor (adjusted odds ratio [aOR], 11.96; 95% confidence interval [CI], 2.58–55.43; P = 0.002), moderate (aOR, 4.66; 95% CI, 2.11–10.28; P < .001), and good (aOR, 7.71; 95% CI, 2.20–27.02; P = 0.001) BATMAN score subgroups. MT was also associated with low mortality rates in the poor (aOR, 0.10; 95% CI, 0.04–0.27; P < 0.001) and moderate (aOR, 0.31; 95% CI, 0.16–0.57; P = 0.002) BATMAN score subgroups. The BATMAN score was significantly associated with favorable outcomes in both the SMT (aOR, 1.44; 95% CI, 1.08–1.93; P = 0.014) and MT (aOR, 1.31; 95% CI, 1.20–1.44; P < 0.001) groups. Higher BATMAN scores were associated with improved prognosis and lower mortality rates after 3 months. MT was associated with improved outcomes in patients with low BATMAN scores despite their worse overall outcomes. ChiCTR1800014759, 2018/02/03.
               
Click one of the above tabs to view related content.