LAUSR

The most common causes of diaphoresis in patients receiving dialysis are related to various types of infections, particularly catheter-associated infections. Fever can result in diaphoresis and an increase in insensible losses leading to hypernatremia. Less common causes of diaphoresis may include endocrine causes (hyperthyroidism, hypoglycemia), occult malignancy, and certain medications. Notably, the two patients we describe had persistent diaphoresis in the absence of fevers or identifiable infectious sources. Given the concern for possible medication toxicity in the first case, bethanechol and diphenhydramine were discontinued. His diaphoresis resolved within 1 day, and his serum sodium corrected. The diphenhydramine was resumed without recurrence of symptoms. The second case had repeated episodes of profuse diaphoresis, and eventually the bethanechol was discontinued with prompt resolution of symptoms and hypernatremia. Discussion