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Children born with congenital anomalies of the kidney and urinary tract (CAKUT) are at risk of progressive chronic kidney disease (CKD) and long-term kidney injury [1, 2]. These observations are… Click to show full abstract
Children born with congenital anomalies of the kidney and urinary tract (CAKUT) are at risk of progressive chronic kidney disease (CKD) and long-term kidney injury [1, 2]. These observations are supported by long-term observational data; however, reports are limited and some are hampered by their retrospective nature, small cohort sizes, short follow ups, and heterogeneous patient populations [3]. Although a variety of CAKUT conditions are thought to have universally good long-term outcomes, such as children born with a solitary functioning kidney due to contralateral renal agenesis or a multicystic dysplastic kidney, a progressive decline in kidney function over time has been reported [4].
Journal Title: Pediatric Nephrology
Year Published: 2020
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