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High BIS and low rSO2 during CPB: seizure?

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During cardiac surgery, anesthetists monitor the bispectral index (BIS) and regional cerebral oxygen saturation (rSO2). We report the case of a high BIS score and low rSO2 value during an… Click to show full abstract

During cardiac surgery, anesthetists monitor the bispectral index (BIS) and regional cerebral oxygen saturation (rSO2). We report the case of a high BIS score and low rSO2 value during an ascending aorta graft surgery. Anesthesia was maintained with propofol and remifentanil infusion. Imme‐ diately after the aortic cross clamp was applied, the BIS abruptly increased to 92, and the rSO2 gradually decreased to 37 on both sides. Midazolam and rocuronium were admin‐ istered, but little change was observed. Vital signs and an arterial blood gas analysis (ABGA) did not show any prob‐ lems. The body temperature was 28 °C. About 20 min after the high BIS, the perfusionist began the sevoflurane inhala‐ tion via a pump. The BIS then decreased to 40, and the rSO2 slowly increased to above 50. The patient was confused and irritable for 3 days after surgery, but did not show any kind of neurological complications thereafter. He did not recall the surgical experience. After we ruled out several causes for the aberrant values, we concluded that a seizure might have occurred during the event. Intraoperative seizures have been reported intermit‐ tently [1, 2]. During a seizure, cerebral activity is exagger‐ ated and coincides with high electromyography activity, resulting in increased BIS values. When a seizure stops, the BIS decreases to the previous level. The rSO2 decreases because of a high metabolic process in the cerebral hemi‐ sphere. After a seizure, the rSO2 increases.

Keywords: low rso2; rso2; bis low; bis; seizure; high bis

Journal Title: Journal of Anesthesia
Year Published: 2018

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