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Intracranial pressure monitoring in diffuse brain injury—why the developing world needs it more?

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BackgroundUse of ICP monitoring is considered to be part of “standard of care” in management of severe traumatic brain injury, but it is rarely used in developing countries. The authors… Click to show full abstract

BackgroundUse of ICP monitoring is considered to be part of “standard of care” in management of severe traumatic brain injury, but it is rarely used in developing countries. The authors present a study which evaluates the efficacy and outcomes of ICP monitoring at a high-volume trauma center in India.MethodsData on management and outcomes for 126 patients who were admitted with diffuse traumatic brain injury (GCS 3–8) were studied prospectively over an 18-month period. These patients were treated by one of the two specific protocols: ICP monitoring-based or non-ICP monitoring-based. The primary outcome was measured based on 2 weeks mortality and GOS-E at 1, 3, and 6 months. Secondary outcome was measured based on need for brain-specific treatment, length of ICU stay, and radiation exposure.ResultsMortality in a subset of patients who underwent surgical intervention later due to increased ICP values, drop in GCS, or radiological deterioration was noted to be significantly lower in the ICP monitoring group (p = 0.03), in spite of statistically insignificant difference in overall mortality rates between groups. GOS-E scores at 1 month were significantly better (p = 0.033) in ICP monitoring group, even though they equalized at 3 and 6 months. The need for brain-specific treatment (p < 0.001), radiation exposure (p < 0.001), and length of ICU stay (p = 0.013) was significantly lower in the ICP monitoring group.ConclusionsICP monitoring-based treatment protocol helps in achieving faster recovery; lowers mortality rates in operated patients; and reduces ICU stay, radiation exposure, and the need for brain-specific treatment.

Keywords: icp monitoring; treatment; monitoring; brain injury; brain

Journal Title: Acta Neurochirurgica
Year Published: 2018

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