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Periodic quadriplegia during the acute postoperative phase of cervical laminoplasty: a case report and literature review

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The use of antibiotics can, in rare cases, induce neuromuscular blockade (NMB), resulting in paralytic symptoms. Although such antibiotic-induced NMB has been described in the anaesthesiology and infectious disease literature,… Click to show full abstract

The use of antibiotics can, in rare cases, induce neuromuscular blockade (NMB), resulting in paralytic symptoms. Although such antibiotic-induced NMB has been described in the anaesthesiology and infectious disease literature, it is an unfamiliar clinical entity in the fields of neurosurgery and spinal surgery. Herein, we report a case of periodic quadriplegia due to NMB induced by perioperative prophylactic antibiotic of cefazolin, resulting in highly confusing paralytic symptoms during the acute postoperative phase of cervical laminoplasty, together with a review of the relevant literature.

Keywords: cervical laminoplasty; phase cervical; periodic quadriplegia; acute postoperative; literature; postoperative phase

Journal Title: Acta Neurochirurgica
Year Published: 2022

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