Eight Vietnamese Newcastle disease virus field isolates from 2008–2015 and 3 vaccine specimens were genotyped based on their full F gene sequences and compared to 80 reference strains representing all… Click to show full abstract
Eight Vietnamese Newcastle disease virus field isolates from 2008–2015 and 3 vaccine specimens were genotyped based on their full F gene sequences and compared to 80 reference strains representing all 18 genotypes. Three isolates formed a novel subgenotype XIId, identified for the first time in Vietnam; while the others clustered as follows: four in subgenotypes VIId and VIIh; two in Genotype I; and two in Genotype II. Evolutionary distance calculations confirmed the Vietnamese XIId isolates were distinct from XIIa and XIIb by 0.062–0.070; and from other genotypes by 0.089–0.245. This data demonstrated that a novel XIId subgenotype emerged in Vietnam indicating considerable genetic diversity, thus highlighting the need to implement antigenic matching during vaccination against NDVs.
               
Click one of the above tabs to view related content.