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We sequenced a portion of the E1 envelope protein gene of two of four CHIKV RT-PCR-positive samples from the first cluster of chikungunya patients during the 2020 Chad outbreak. Phylogenetic… Click to show full abstract
We sequenced a portion of the E1 envelope protein gene of two of four CHIKV RT-PCR-positive samples from the first cluster of chikungunya patients during the 2020 Chad outbreak. Phylogenetic analysis revealed that the viruses belonged to the East/Central/South/African genotype but lacked the E1 A226V and K211E mutations associated with viral adaptability and transmission, suggesting an autochthonous transmission. These sequences are a useful basis for tracking viral evolution in subsequent outbreaks in Chad.
Keywords:
characterization chikungunya;
molecular characterization;
first cluster;
patients 2020;
chikungunya virus
Journal Title: Archives of virology
Year Published: 2022
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Journal Title: Archives of virology
Year Published: 2022
Link to full text (if available)
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recommendations!