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A permissible region strategy for fluorescence molecular tomography

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A large-scale fluorescence measurement captured by non-contact fluorescence molecular tomography imaging system is utilized to reconstruct the three-dimensional distribution of fluorescent probe in small animals. However, this makes the computational… Click to show full abstract

A large-scale fluorescence measurement captured by non-contact fluorescence molecular tomography imaging system is utilized to reconstruct the three-dimensional distribution of fluorescent probe in small animals. However, this makes the computational burden heavier and restricts the capacity of this technique. In general, the extracting area of interest is a universal method of increasing the effectiveness of the reconstruction. Hence, this study proposed permissible region extraction strategy by means of the node with the maximum energy at each projection. Simulation experiment and physical experiment demonstrated that the presented method can provide high-graded images at a shorter time cost. Furthermore, the stability of this method deserves investigation even under quite ill-posed conditions.

Keywords: fluorescence; molecular tomography; fluorescence molecular; permissible region

Journal Title: Optical Review
Year Published: 2019

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