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IgG antibodies against myelin oligodendrocyte glycoprotein (MOG) are associated with acute demyelinating encephalomyelitis [1], neuromyelitis optica, cortical encephalitis [2, 3], or aseptic meningitis [4]. MOG-antibodies are usually examined in serum… Click to show full abstract
IgG antibodies against myelin oligodendrocyte glycoprotein (MOG) are associated with acute demyelinating encephalomyelitis [1], neuromyelitis optica, cortical encephalitis [2, 3], or aseptic meningitis [4]. MOG-antibodies are usually examined in serum but rarely detected exclusively in cerebrospinal fluid (CSF) [5]. The antibodies can be detected in patients with overlapping demyelinating syndromes and anti-NMDA receptor (NMDAR) encephalitis [6–8], but the role of CSF MOG-antibodies in patients with NMDAR-antibody-positive aseptic meningitis remains unclear. Herein, we report a case of recurrent antiNMDAR encephalitis with leptomeningeal enhancement, in which MOG-antibodies were retrospectively identified in the CSF. Case presentation
Journal Title: Neurological Sciences
Year Published: 2020
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