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Covid-19-associated acute haemorrhagic leukoencephalomyelitis

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Dear Editor, Neurological symptoms in Covid-19 involving central and peripheral nervous system have been reported with varying frequency. The importance of identifying neurological symptoms cannot be overemphasised by the fact… Click to show full abstract

Dear Editor, Neurological symptoms in Covid-19 involving central and peripheral nervous system have been reported with varying frequency. The importance of identifying neurological symptoms cannot be overemphasised by the fact that loss of sense of smell is now considered one of the earliest features of Covid-19 [1]. Although impaired consciousness has been reported in approximately 17% patients with Covid-19, acute haemorrhagic leukoencephalomyelitis (AHL) as its cause has been reported in very few cases [2]. AHL is characterised by rapidly progressive, fulminant inflammatory haemorrhagic demyelination mainly involving the white matter and is almost always monophasic. Aetiology is most likely post infectious and is usually associated with poor prognosis [3]. We h e r e i n r e p o r t a c a s e o f a c u t e h a emo r r h a g i c leukoencephalomyelitis secondary to Covid-19 from a tertiary care centre in India. To the best of our knowledge, this is the first case of Covid-19-associated AHL to be reported from India.

Keywords: acute haemorrhagic; haemorrhagic leukoencephalomyelitis; leukoencephalomyelitis; covid associated

Journal Title: Neurological Sciences
Year Published: 2020

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