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Factors Associated with PrEP Refusal Among Transgender Women in Northeastern Brazil

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Brazil has recently integrated HIV Pre-exposure Prophylaxis (PrEP) into its public health system and offered to key populations such as transgender women (TGW). This study investigates factors associated with PrEP… Click to show full abstract

Brazil has recently integrated HIV Pre-exposure Prophylaxis (PrEP) into its public health system and offered to key populations such as transgender women (TGW). This study investigates factors associated with PrEP refusal among TGW living in one of the largest and poorest cities of Brazil. We recruited 127 TGW using Respondent Driven Sampling (RDS) in Salvador, Brazil. Latent class analysis (LCA) was used to define acceptability of PrEP. Two latent classes were identified: “high acceptability of PrEP” (91.3%) and “PrEP refusal” (8.7%). PrEP was less acceptable among white TGW and among those age 25 or older, with income above minimum wage (≥ US$252.87), and reporting unprotected receptive anal intercourse with (URAI) causal partners. The findings highlight how nuanced strategies that takes into consideration unique characteristics are needed to effectively address the acceptability of PrEP.ResumenBrasil ha integrado recientemente la Profilaxis de Preexposición (PrEP) ao VIH en su sistema de salud pública y se ofrece a las poblaciones claves como las mujeres transgénero (TGW). Este estudio investiga los factores asociados al rechazo de la PrEP entre las TGW que viven en una de las ciudades más grandes y más pobres de Brasil. Reclutamos 127 TGW utilizando Respondent Driven Sampling (RDS) en Salvador, Brasil. El análisis de clase latente (LCA) se usó para definir la aceptabilidad de PrEP. Se identificaron dos clases latentes: “alta aceptabilidad de PrEP” (91.3%) y “recusa da PrEP” (8.7%). La PrEP fue menos aceptable entre las TGW de piel blanca, de 25 años o más, con ingresos de > $ 252.87 dólares y con relaciones anales receptivas no protegidas con parejas casuales (RARNP). La PrEP fue muy aceptable en esta muestra de las TGW en el nordeste de Brasil. Sin embargo, las TGW con mayor riesgo de infección por VIH, que generalmente tienen RARNP, estaban menos dispuestas a usar PrEP.

Keywords: prep; transgender women; prep refusal; tgw; factors associated

Journal Title: AIDS and Behavior
Year Published: 2019

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