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Activation of lysosomal proteolysis and increased coenzyme Q10 level were revealed in the liver and brain of rats with individual typological features under conditions of food deprivation. Changes in cathepsin… Click to show full abstract
Activation of lysosomal proteolysis and increased coenzyme Q10 level were revealed in the liver and brain of rats with individual typological features under conditions of food deprivation. Changes in cathepsin B activity in these tissues were different in behaviorally active and passive animals. We observed indirect modulating effect of coenzyme Q10 in the regulation of activity of lysosomal endopeptidases in the brain of animals with different behavior during adaptation to metabolic stress.
Keywords:
lysosomal proteolysis;
metabolic stress;
liver brain;
brain rats;
brain
Journal Title: Bulletin of Experimental Biology and Medicine
Year Published: 2018
Link to full text (if available)
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Journal Title: Bulletin of Experimental Biology and Medicine
Year Published: 2018
Link to full text (if available)
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recommendations!