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Amending the Efficiency of Antimicrobials against Multidrug-Resistant Pseudomonas aeruginosa by Low-Frequency Magnetic Fields.

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We studied the effect of 1- and 2-h exposure to low-frequency magnetic fields (0.3 and 0.42 mT) on the sensitivity of Pseudomonas aeruginosa to 18 antibiotics. P. aeruginosa samples were… Click to show full abstract

We studied the effect of 1- and 2-h exposure to low-frequency magnetic fields (0.3 and 0.42 mT) on the sensitivity of Pseudomonas aeruginosa to 18 antibiotics. P. aeruginosa samples were obtained from 20 patients with burns. Exposure to magnetic field reduced the resistance of P. aeruginosa and increased their susceptibility to antimicrobial drugs. This increase was positively correlated with field intensity and duration of exposure. After 2-h exposure to 0.42 mT, susceptibility of P. aeruginosa to antimicrobial drugs aztreonam, ceftazidime, colistin, imipenem, levofloxacin, and meropenem significantly increased. In addition, resensitization of P. aeruginosa to carbapenems, penicillin, quinolones, and aminoglycosides groups was observed.

Keywords: magnetic fields; pseudomonas aeruginosa; frequency magnetic; amending efficiency; low frequency

Journal Title: Bulletin of experimental biology and medicine
Year Published: 2020

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