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Mesenchymal stem cells (MSC), like macrophages, can be polarized in vitro . In particular, activation of type 4 Toll-like receptor in MSC leads to the appearance of the so-called “proinflammatory”… Click to show full abstract
Mesenchymal stem cells (MSC), like macrophages, can be polarized in vitro . In particular, activation of type 4 Toll-like receptor in MSC leads to the appearance of the so-called “proinflammatory” MSC phenotype (MSC1). We showed that secretome (conditioned media) of MSC1 can affect the wound healing processes: promote healing and modulate exudative inflammation and subsequent fibroplastic processes in the damaged area. These effects of secretomes of polarized MSC were superior to those of intact MSC.
Keywords:
msc;
stem cells;
activation tlr4;
mesenchymal stem
Journal Title: Bulletin of Experimental Biology and Medicine
Year Published: 2021
Link to full text (if available)
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Journal Title: Bulletin of Experimental Biology and Medicine
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!