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A new sight: topology-dependent mitophagy

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Abbreviations BCL2L13 BCL2-like 13 BNIP3 BCL2-interacting protein 3 BNIP3L/NIX BCL2-interacting protein 3 like CALCOCO2/NDP52 Calcium-binding and coiled-coil domain 2 FUNDC1 FUN14 domain-containing 1 GABARAP Gamma-aminobutyric acid receptor–associated protein LIR LC3-interacting… Click to show full abstract

Abbreviations BCL2L13 BCL2-like 13 BNIP3 BCL2-interacting protein 3 BNIP3L/NIX BCL2-interacting protein 3 like CALCOCO2/NDP52 Calcium-binding and coiled-coil domain 2 FUNDC1 FUN14 domain-containing 1 GABARAP Gamma-aminobutyric acid receptor–associated protein LIR LC3-interacting region MAP 1LC3/LC3 Microtubule-associated protein 1 light chain 3 MFN1 mitofusin 1 MFN2 Mitofusin 2 mPTP Mitochondrial permeability transition pore NBR1 NBR1 autophagy cargo receptor OPTN Optineurin PHB2 Prohibitin 2 PINK1 PTEN-induced putative kinase 1 PRKN/PARKIN parkin RBR E3 ubiquitin protein ligase P62/SQSTM1 Sequestosome 1 ROS Reactive oxygen species TBK1 Tank-binding kinase 1 ΔΨm Mitochondrial membrane potential

Keywords: protein; sight topology; topology dependent; dependent mitophagy; topology; new sight

Journal Title: Cell Biology and Toxicology
Year Published: 2020

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