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Synthesis of Polycyclic (Hetero)Aromatic Hydrocarbons via the Friedel–Crafts/Bradsher Cyclization

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This review covers the literature on synthesis of polycyclic aromatic hydrocarbons via the Friedel–Crafts/Bradsher cyclization, published in the period of 1987–2016. Syntheses of partly and fully fused (hetero)aromatic systems with… Click to show full abstract

This review covers the literature on synthesis of polycyclic aromatic hydrocarbons via the Friedel–Crafts/Bradsher cyclization, published in the period of 1987–2016. Syntheses of partly and fully fused (hetero)aromatic systems with 5- or 6-membered rings formed upon the cyclization and containing C, O, S, N ring (hetero)atoms are reported in this work. All described aromatic systems have been formed in reactions using aromatic aldehydes and their derivatives as carbonyl reagents.

Keywords: via friedel; synthesis polycyclic; cyclization; hydrocarbons via; hetero; aromatic hydrocarbons

Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2017

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