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Acid-catalyzed reaction of phenols with N-(4,4-diethoxybutyl)sulfonamides – a new method for the synthesis of 2-aryl-1-sulfonylpyrrolidines

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We have developed a new method for the synthesis of 2-aryl-1-sulfonylpyrrolidines on the basis of reactions between various phenols and N-(4,4-diethoxybutyl)sulfonamides in the presence of trifluoroacetic acid. The structures of… Click to show full abstract

We have developed a new method for the synthesis of 2-aryl-1-sulfonylpyrrolidines on the basis of reactions between various phenols and N-(4,4-diethoxybutyl)sulfonamides in the presence of trifluoroacetic acid. The structures of the obtained products were confirmed by 1H and 13C NMR spectroscopy, IR spectroscopy, and X-ray structural analysis.

Keywords: phenols diethoxybutyl; new method; aryl sulfonylpyrrolidines; spectroscopy; method synthesis; synthesis aryl

Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2017

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