The minireview provides a survey of combretastatin A-4 analogs, obtained by isosteric replacement of 3-hydroxy-4-methoxyphenyl ring (ring B) with various heterocyclic systems. The basic synthetic approaches and structure–activity relationships are… Click to show full abstract
The minireview provides a survey of combretastatin A-4 analogs, obtained by isosteric replacement of 3-hydroxy-4-methoxyphenyl ring (ring B) with various heterocyclic systems. The basic synthetic approaches and structure–activity relationships are summarized.
Keywords:
isosters combretastatin;
ring isosters;
nonclassical ring;
classical nonclassical;
chemistry;
heterocycles classical
Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2017
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Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2017
Link to full text (if available)
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recommendations!