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Synthesis of 5-azido-3-nitro-1H-1,2,4-triazole by using a cyanoethyl activating group

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A new method is proposed for the preparation of 5-azido-3-nitro-1H-1,2,4-triazole, based on cyanoethylation of 5-bromo-3-nitro-1H-1,2,4-triazole, nucleophilic substitution of bromide with azide ion, and removal of cyanoethyl protecting group. Click to show full abstract

A new method is proposed for the preparation of 5-azido-3-nitro-1H-1,2,4-triazole, based on cyanoethylation of 5-bromo-3-nitro-1H-1,2,4-triazole, nucleophilic substitution of bromide with azide ion, and removal of cyanoethyl protecting group.

Keywords: azido nitro; synthesis azido; group; nitro triazole

Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2017

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