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Synthesis of polyfunctionalized 1,1'-(α,ω-alkanediyl)bis(1,2,3,4-tetrahydropyridines)

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A one-pot reaction was developed for the synthesis of polyfunctionalized 1,1'-(α,ω-alkanediyl)bis(1,2,3,4-tetrahydropyridines) in 28–69% yields on the basis of a three-component reaction between 1,3-dicarbonyl compounds, aqueous 33% solution of formaldehyde, and… Click to show full abstract

A one-pot reaction was developed for the synthesis of polyfunctionalized 1,1'-(α,ω-alkanediyl)bis(1,2,3,4-tetrahydropyridines) in 28–69% yields on the basis of a three-component reaction between 1,3-dicarbonyl compounds, aqueous 33% solution of formaldehyde, and α,ω-diamines.

Keywords: polyfunctionalized alkanediyl; alkanediyl bis; bis tetrahydropyridines; synthesis polyfunctionalized

Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2017

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