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Synthesis of functionalized triazolo[1,5-a]pyrimidine derivatives

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New triazolo[1,5-a]pyrimidines containing aroyl and acetyl or ester groups in the pyrimidine ring were synthesized in a process related to the Biginelli-like reaction, using hydrates of arylglyoxals, β-dicarbonyl compounds, and… Click to show full abstract

New triazolo[1,5-a]pyrimidines containing aroyl and acetyl or ester groups in the pyrimidine ring were synthesized in a process related to the Biginelli-like reaction, using hydrates of arylglyoxals, β-dicarbonyl compounds, and 1H-1,2,4-triazol-5-amine. Reaction was carried out in either sequential or one-pot procedure.

Keywords: triazolo pyrimidine; synthesis functionalized; chemistry; pyrimidine derivatives; functionalized triazolo

Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2018

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