The corresponding ethyl 5-carbonylglycinates were synthesized by condensation of 4-(Boc-amino)-1,2,3-triazole-5-carboxylic acids with ethyl glycinate hydrochloride. They were intramolecularly cyclized with the selective formation of 1,4,6,7-tetrahydro[1,2,3]triazolo[4,5-e]- [1,4]diazepine-5,8-diones. Click to show full abstract
The corresponding ethyl 5-carbonylglycinates were synthesized by condensation of 4-(Boc-amino)-1,2,3-triazole-5-carboxylic acids with ethyl glycinate hydrochloride. They were intramolecularly cyclized with the selective formation of 1,4,6,7-tetrahydro[1,2,3]triazolo[4,5-e]- [1,4]diazepine-5,8-diones.
               
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