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Bridged 1,2,4,5-tetraoxanes were prepared using available acidic ion exchange resin with high yields despite the possibility of peroxide decomposition under heterogeneous conditions. The bridged tetraoxanes demonstrated high cytotoxicity against HeLa… Click to show full abstract
Bridged 1,2,4,5-tetraoxanes were prepared using available acidic ion exchange resin with high yields despite the possibility of peroxide decomposition under heterogeneous conditions. The bridged tetraoxanes demonstrated high cytotoxicity against HeLa cancer cells in vitro, which in some cases was higher than that of cisplatin, artesunate, and dihydroartemisinin.
Keywords:
cytotoxicity hela;
exchange resin;
ion exchange;
cancer cells;
hela cancer;
bridged tetraoxanes
Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2020
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Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!