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Regularization Methods in the Analysis of a Series of Scintillation Fluorescence Microscopy Images

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We consider the construction of high-resolution images from a time series of fluorescence microscopy images obtained using a scintillator. A regularization method is applied and the results are compared for… Click to show full abstract

We consider the construction of high-resolution images from a time series of fluorescence microscopy images obtained using a scintillator. A regularization method is applied and the results are compared for various stabilizers, including the RED (regularization-by-denoising) approach. Tests conducted for two series of microtubule structures have proved the applicability of the proposed methods.

Keywords: microscopy; regularization methods; fluorescence microscopy; microscopy images; series

Journal Title: Computational Mathematics and Modeling
Year Published: 2021

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