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Prenylated Isocoumarins from the Fermentation Products of the Endophytic Fungus Aspergillus versicolor and Their Anti-Tobacco Mosaic Virus Activities

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Two new prenylated isocoumarins, versicolols C and D (1 and 2), together with three known isocoumarins (3–5), were isolated from the fermentation products of the endophytic fungus Aspergillus versicolor. Their… Click to show full abstract

Two new prenylated isocoumarins, versicolols C and D (1 and 2), together with three known isocoumarins (3–5), were isolated from the fermentation products of the endophytic fungus Aspergillus versicolor. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. The anti-tobacco mosaic virus (anti-TMV) activities of compounds 1 and 2 were evaluated. The results revealed that compounds 1 and 2 showed moderate anti-TMV activity with inhibition rates of 22.4 and 24.6%, respectively.

Keywords: endophytic fungus; aspergillus versicolor; fermentation products; fungus aspergillus; prenylated isocoumarins; products endophytic

Journal Title: Chemistry of Natural Compounds
Year Published: 2017

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