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Eight alkaloidal constituents have been isolated and structurally elucidated from Cephalotaxus mannii Hook. f. collected from the highland Lam Dong Province, Vietnam. They are: cephalotaxine (1), isoharringtonine (2), norisoharringtonine (3),… Click to show full abstract
Eight alkaloidal constituents have been isolated and structurally elucidated from Cephalotaxus mannii Hook. f. collected from the highland Lam Dong Province, Vietnam. They are: cephalotaxine (1), isoharringtonine (2), norisoharringtonine (3), desoxyharringtonine (4), nordesoxyharringtonine (5), cephalotaxine ???? -N-oxide (6), 3-epi-schellhammericine (7), and an isomer of 3-epi-schellhammericine (8). Among them, norisoharringtonine (3) is a new compound, while the other compounds are isolated from C. mannii for the first time. The structures of these constituents were determined by spectroscopic methods such as FTIR, ESI-MS, HR-ESI-MS, and NMR (1D, 2D) and by comparison with published data.
Journal Title: Chemistry of Natural Compounds
Year Published: 2017
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