LAUSR

Eurotium, a common fungus closely related to human life, is adapted to high osmotic pressure and can adapt to a low water environment [1]. They are dominant microorganisms that are found during the molding process in the manufacture of Japanese Katsuobushi [2] and Chinese Fuzhuan brick-tea [3]. Eurotium sp. are a rich source of bioactive secondary metabolites, such as anthraquinones, benzaldehydes, and diketopiperazines [1]. Some of these metabolites possess antimicrobial [4], antitumor [5], anti-inflammatory [6], and cytotoxic activities [7], as well as antioxidant properties [5], and the ability to degrade pesticide residues [8], among others. Therefore, a comprehensive understanding of the characteristics and secondary metabolites of Eurotium would lay a foundation for the reasonable utilization of its resources. Herein, we report the isolation, structural characterization, and biological activities of these compounds. On the basis of spectral data and by comparison with those reported in the literature, the structures of compounds 1–8 were established as neoechinulin A (1) [9], L-alanyl-L-tryptophan anhydride (2) [10], dihydroxyisoechinulin A (3) [11], questin (4) [12], questinol (5) [13], variecolorquinone A (6) [14], asperflavin (7) [15], and isotorachrysone-6-O-Dribofuranoside (8) [16].