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Polysaccharide fractions were sequentially extracted in 28.86 wt% yield from roots of Ferula sinkiangensis K. M. Shen. The polysaccharide fractions from F. sinkiangensis were identified as heteropolysaccharides and contained primarily… Click to show full abstract
Polysaccharide fractions were sequentially extracted in 28.86 wt% yield from roots of Ferula sinkiangensis K. M. Shen. The polysaccharide fractions from F. sinkiangensis were identified as heteropolysaccharides and contained primarily the monosaccharides glucuronic and galacturonic acids, rhamnose, xylose, arabinose, galactose, and fructose. The isolated polysaccharide fractions at low concentrations exhibited in vitro inhibitory activity for protein-tyrosine phosphatase 1B. The degree of inhibition correlated with the galactose content in the polysaccharide fractions.
Journal Title: Chemistry of Natural Compounds
Year Published: 2019
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