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A New Flavone from Flos Sophorae Immaturus Through Microbial Transformation by Nigrospora sphaerica ZMT05

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A new flavone derivative, 3′-(γ,γ-dimethylallyloxy)-5,7-dihydroxy-4′-methoxyflavone (1), was isolated from Flos Sophorae Immaturus through microbial transformation by the fungus Nigrospora sphaerica ZMT05. Its structure was elucidated by comprehensive spectroscopic analyses. This… Click to show full abstract

A new flavone derivative, 3′-(γ,γ-dimethylallyloxy)-5,7-dihydroxy-4′-methoxyflavone (1), was isolated from Flos Sophorae Immaturus through microbial transformation by the fungus Nigrospora sphaerica ZMT05. Its structure was elucidated by comprehensive spectroscopic analyses. This compound showed moderate in vitro antifungal activities against Colletotrichum musae and Penicillium italicum.

Keywords: microbial transformation; flos sophorae; immaturus microbial; sophorae immaturus; nigrospora sphaerica; new flavone

Journal Title: Chemistry of Natural Compounds
Year Published: 2019

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