The genus Lindera consists of 100 species widely grown in tropical and subtropical areas. This genus has interesting pharmacological properties such as anticancer and anti-inflammatory activities. Previous phytochemical investigations on… Click to show full abstract
The genus Lindera consists of 100 species widely grown in tropical and subtropical areas. This genus has interesting pharmacological properties such as anticancer and anti-inflammatory activities. Previous phytochemical investigations on Lindera plants revealed the presence of sesquiterpenoids, alkaloids, butanolides, flavonoids, phenylpropanoids, and lucidones [1]. Lindera myrrha (Lour.) Merr. is widely distributed in the South of Vietnam. It is used for traditional Vietnamese medicine to relieve gastric pains, rheumatism, and as an anti-emetic drug [2, 3]. Previous phytochemical studies on the roots of this plant revealed the presence of nine aporphine alkaloids [3]. However, there are no reports regarding other phytochemical constituents of this plant. Herein, we describe the procedure for the isolation and identification of nine sesquiterpenoids from L. myrrha roots; linderane (1), linderalactone (2), lindenenol A (3), lindenenyl acetate (4), strychnistenolides A and B (5a and 5b), 6-O-acetate strychnistenolides A and B (6a and 6b), and pseudoneoliacine (7). To the best of our knowledge, all isolated sesquiterpenoids (1–7) were isolated from this species for the first time.
               
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