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A New Compound from Polygonum amplexicaule var. sinense

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One new phenyl group dimeric compound, named polygamol A (1), together with two known compounds, 2,2-bis[4-(2,3-dihydroxypropoxy)phenyl]propane (2) and 1,3-di-O-[2′,2′-di-(p-phenylene)isopropylidene]-glycerol (3), were isolated from the roots of Polygonum amplexicaule var. sinense.… Click to show full abstract

One new phenyl group dimeric compound, named polygamol A (1), together with two known compounds, 2,2-bis[4-(2,3-dihydroxypropoxy)phenyl]propane (2) and 1,3-di-O-[2′,2′-di-(p-phenylene)isopropylidene]-glycerol (3), were isolated from the roots of Polygonum amplexicaule var. sinense. The structures of these compounds were elucidated based on spectroscopic analysis. The new compound exhibited weak activity in vitro against the MGC-803, A549, SMMC-7721, and HT-29 cell lines.

Keywords: new compound; amplexicaule var; polygonum amplexicaule; var sinense; compound

Journal Title: Chemistry of Natural Compounds
Year Published: 2020

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