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Diabetic Hepatosclerosis in a Woman with Maturity-Onset Diabetes of the Young Type 3

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Diabetic hepatosclerosis (DHS), initially described in 2006, represents a form of diabetic microangiopathy of the liver found in patients with long-standing diabetes mellitus with other microvascular complications [1]. DHS is… Click to show full abstract

Diabetic hepatosclerosis (DHS), initially described in 2006, represents a form of diabetic microangiopathy of the liver found in patients with long-standing diabetes mellitus with other microvascular complications [1]. DHS is characterized by hepatic sinusoidal fibrosis with basement membrane formation in the absence of any histological features of nonalcoholic fatty liver disease. [2] There are only limited data regarding the underlying mechanisms, clinical presentation, progression, and prognosis of DHS. In this paper, we report DHS in a young woman with maturity-onset diabetes of the young type 3 (MODY 3) and discuss the current literature on this topic.

Keywords: diabetes young; young type; onset diabetes; maturity onset; diabetic hepatosclerosis; woman maturity

Journal Title: Digestive Diseases and Sciences
Year Published: 2021

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