LAUSR

The use of organochlorine pesticides (OCPs) is a worldwide public health concern given that high levels of these compounds in humans and animals can lead to serious health problems. This study aimed to evaluate the levels of 15 organochlorine pesticides in the serum of 547 blood donors in the São Paulo metropolitan region (SPMR) in 2009 and to investigate factors associated with higher levels of these compounds. The OCPs were determined by gas chromatography with micro electron capture detection. Multiple ordinal logistic regression models were employed to determine the factors associated with higher levels. Only β-HCH and p,p’-DDE had a significant number of samples above the limit of quantification. Factors associated with higher levels of β-HCH were age within 26 to 35 years (OR = 3.1 [1.05–9.09]), age within 36 to 45 years (OR = 18.27 [6.89–48.91]), and female gender (OR = 0.44 [0.24–0.82] for men). p,p’-DDE levels were associated with age within 26 to 35 years (OR = 2.65 [1.20–3.45]), age within 36 to 45 years (OR = 4.59 [2.64–7.92]), female gender (OR = 0.86 [0.43–0.94] for men), and previous work with pesticides (OR = 2.88 [1.22–6.84]). Lower levels of p,p’-DDE were associated with an income of 3 to 5 minimum wages (OR = 0.38 [0.19–0.75]) and with intake of foods from animal origin up to twice a week (OR = 0.15 [0.03–0.72]) and more than twice a week (OR = 0.10 [0.02–0.47]). The results of this study indicate that the study group was not exposed to high levels of OCPs.