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Antimicrobial, Cytotoxicity and Photocatalytic Degradation of Norfloxacin Using Kleinia grandiflora Mediated Silver Nanoparticles

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Synthesis of nanomaterials through green and eco-friendly approaches which are free from toxic chemicals is an emerging interest in the field of nanoscience and nanotechnology. Plant-mediated synthesis of silver nanoparticles… Click to show full abstract

Synthesis of nanomaterials through green and eco-friendly approaches which are free from toxic chemicals is an emerging interest in the field of nanoscience and nanotechnology. Plant-mediated synthesis of silver nanoparticles (AgNPs) gained importance because of its non-toxic, eco-friendly and potential for biomedical applications. The present study explored the synthesis of AgNPs using Kleinia grandiflora leaf extract (KGLE) as a reducing and stabilizing agent. The synthesized AgNPs were characterized via UV–Vis spectroscopy (UV–Vis), Fourier transform-infrared spectroscopy, X-ray diffraction, scanning electron microscopy, transmission electron microscopy and energy dispersive X-ray spectroscopy. The biosynthesized AgNPs were found to be spherical in shape and particle size in the range of 20–50 nm. Besides, the synthesized AgNPs showed significant antimicrobial efficacy against Pseudomonas aeruginosa and Aspergillus niger as well as considerable cytotoxicity towards Dalton’s lymphoma ascites cells with 100% inhibition at the concentration of 200 µg/mL of Ag-NPs. Furthermore, the photocatalytic degradation of norfloxacin under visible light irradiation explored the better reducing ability after 80 min of exposure time It is envisioned that KGLE mediated synthesized AgNPs may have a better antimicrobial, cytotoxic and photocatalytic agent in future.

Keywords: silver nanoparticles; microscopy; kleinia grandiflora; spectroscopy; using kleinia; photocatalytic degradation

Journal Title: Journal of Cluster Science
Year Published: 2019

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